HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Difluorocyclopropane-1-carboxylic acid → HCID 178523634, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Difluorocyclopropane-1-carboxylic acid | HCID 2782823 | — |
| Reactant | HCID 178478713 | HCID 178478713 | — |
| Product | HCID 178523634 | HCID 178523634 | — |
Reaction Steps
The title compound, light brown solid (81 mg, 75%), MS (ISP) m/z=431.4 [(M+H)+], mp 189° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 2,2-difluoro-cyclopropane-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921397B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-51e0a65eef784f4e823c37e7c0d48461 |
| Source note | uspto-grants-2014_12 |