3-Hydroxyisovaleric acid → HCID 178459208, compound

Participants

Reaction Steps

The title compound, light yellow solid (59 mg, 55%), MS (ISP) m/z=427.3 [(M+H)+], mp 150° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 3-hydroxy-3-methyl-butyric acid.

Provenance & Evidence