tert-Butylacetic acid → HCID 178445241, compound

Participants

Reaction Steps

The title compound, off-white solid (83 mg, 78%), MS (ISP) m/z=425.3 [(M+H)+], mp 174° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 3,3-dimethyl-butyric acid.

Provenance & Evidence