Methyl (S)-3-hydroxypentanoate → HCID 178456101, compound

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Reaction Steps

The title compound, white solid (99 mg, 93%), MS (ISP) m/z=427.3 [(M+H)+], mp 140° C., was prepared in accordance with the general method of example 46 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and (S)-methyl 3-hydroxypentanoate.

Provenance & Evidence