trans-3-pentenoic acid → HCID 178447382, compound

Participants

Reaction Steps

The title compound, white solid (71 mg, 70%), MS (ISP) m/z=409.4 [(M+H)+], mp 165° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and (E)-pent-3-enoic acid.

Provenance & Evidence