HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Benzodioxole-5-carboxylic acid → HCID 178523636, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Benzodioxole-5-carboxylic acid | HCID 7196 | — |
| Reactant | HCID 178478713 | HCID 178478713 | — |
| Product | HCID 178523636 | HCID 178523636 | — |
Reaction Steps
The title compound, off-white solid (97 mg, 82%), MS (ISP) m/z=475.3 [(M+H)+], mp 198° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and benzo[1,3]dioxole-5-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921397B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-dae2215a0db04c1d9f65f35fe38a60f8 |
| Source note | uspto-grants-2014_12 |