4-tert-Butylbenzoic acid → HCID 178440968, compound

Participants

Reaction Steps

The title compound, yellow solid (110 mg, 90%), MS (ISP) m/z=487.5 [(M+H)+], mp 180° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 4-tert-butyl-benzoic acid.

Provenance & Evidence