Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409921Generated: October 28, 2026

4-(4-Methylpiperazin-1-yl)benzoic acid → HCID 178480696, compound

https://huagongshe.com/reaction/1409921

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Methylpiperazin-1-yl)benzoic acidHCID 736532—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178480696HCID 178480696—

Reaction Steps

The title compound, off-white solid (56 mg, 42%), MS (ISP) m/z=529.4 [(M+H)+], mp 242° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 4-(4-methyl-piperazin-1-yl)-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-098ff0ce0cbf49f58135e4c169dc48ce
Source noteuspto-grants-2014_12