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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409926Generated: October 31, 2026

5-(Morpholin-4-yl)pyrazine-2-carboxylic acid → HCID 178523659, compound

https://huagongshe.com/reaction/1409926

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Morpholin-4-yl)pyrazine-2-carboxylic acidHCID 45789762—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178523659HCID 178523659—

Reaction Steps

The title compound, off-white solid (95 mg, 73%), MS (ISP) m/z=518.4 [(M+H)+], mp 202° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 5-morpholin-4-yl-pyrazine-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-6a6e0d63608043c8816bed774f94a710
Source noteuspto-grants-2014_12