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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409931Generated: October 31, 2026

6-Quinolinecarboxylic acid → HCID 178523637, compound

https://huagongshe.com/reaction/1409931

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Quinolinecarboxylic acidHCID 82571—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178523637HCID 178523637—

Reaction Steps

The title compound, yellow solid (106 mg, 88%), MS (ISP) m/z=482.4 [(M+H)+], mp 192° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and quinoline-6-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-9be3d94fe9a643958e45d6f767c3e416
Source noteuspto-grants-2014_12