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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1409935Generated: October 31, 2026

1-Adamantanecarboxylic acid → HCID 178523632, compound

https://huagongshe.com/reaction/1409935

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Adamantanecarboxylic acidHCID 13235—
ReactantHCID 178478713HCID 178478713—
ProductHCID 178523632HCID 178523632—

Reaction Steps

The title compound, light yellow solid (94 mg, 77%), MS (ISP) m/z=489.4 [(M+H)+], mp 200° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and adamantane-1-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921397B2
Source datasetuspto-grants-2014_12
ORD IDord-17065625f4664a03963b4ef748fb7bc0
Source noteuspto-grants-2014_12