p-(Methylsulphonyl)benzoic acid → HCID 178504773, compound

Participants

Reaction Steps

The title compound, off-white solid (95 mg, 75%), MS (ISP) m/z=509.3 [(M+H)+], mp 224° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-3-yl-piperidin-1-yl)-ethyl]-cyclohexylamine dihydrochloride (intermediate A) (100 mg, 0.25 mmol) and 4-methanesulfonyl-benzoic acid.

Provenance & Evidence