Ethyl diazoacetate → Ethyl 3-(trimethylsilyl)-1H-pyrazole-5-carboxylate

Participants

Reaction Conditions

Reaction Steps

To a flame dried sealed tube equipped with a stir bar that was cooled under argon was added trimethylsilylacetylene (1.0 mL, 9.56 mmol) and ethyldiazoacetate (1.5 mL, 9.6 mmol). The tube was then sealed and heated to 95° C. over night. The next day the reaction was cooled to room temperature and the resulting mixture diluted with hexanes. It was then filtered. The precipitate was then washed with hexanes twice. It was then used without any further purification.

Provenance & Evidence