Ethynylpyridine → Ethyl 3-(pyridin-2-yl)-1H-pyrazole-5-carboxylate

HRID 1409973Notizen

Reaktionsgleichung

C[Si](C)(C)[C:3]1[CH:7]=[C:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[NH:5][N:4]=1.C(OCC=[N+]=[N-])(=O)C.C([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=1)#C>>[N:26]1[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=1[C:3]1[CH:7]=[C:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[NH:5][N:4]=1

Komponenten

Edukt 3

HCID 137268Ethynylpyridine

HCID 54217441Diazoethylacetate

HCID 178469409Ethyl 3-(trimethylsilyl)-1H-pyrazole-5-carboxylate

Produkt 1

HCID 612416Ethyl 3-(pyridin-2-yl)-1H-pyrazole-5-carboxylate

Versuchsvorschrift

Was prepared in a similar way as ethyl 3-(trimethylsilyl)-1H-pyrazole-5-carboxylate using diazoethyl acetate (Purchased from Aldrich) and 2-ethynyl-pyridine (Purchased from Aldrich).

Quellen und Nachweise

ORD-Eintrag: ord-5dc13392560243be88821532bf647aad
Quelldatensatz: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08921401B2

Notizen zur Reaktion

Wird geladen…