6-Chloro-2-piperazin-1-yl-quinoline → 9-{4-[4-(6-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-xanthene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Reaction equation
[Cl:28][c:29]1[cH:30][c:31]2[cH:32][cH:33][c:34]([N:39]3[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]3)[n:35][c:36]2[cH:37][cH:38]1.[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:21][CH2:22][CH2:23][CH2:24][Br:25])[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[O:14][c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]21)([F:26])[F:27]>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:21][CH2:22][CH2:23][CH2:24][N:42]2[CH2:41][CH2:40][N:39]([c:34]3[cH:33][cH:32][c:31]4[cH:30][c:29]([Cl:28])[cH:38][cH:37][c:36]4[n:35]3)[CH2:44][CH2:43]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2[O:14][c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]21)([F:26])[F:27]Participants
3
Sources & evidence
- ORD record
- ord-d6178ca930ba425a9bdb059568af34fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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