HCID 68379113, compound → HCID 68379077, compound

Participants

Reaction Steps

To a solution of 6-(3-nitrophenyl)-2-oxa-6-azaspiro[3.3]heptane (130 mg, 0.59 mmol) in 5 mL of EtOH was added 10% Pd/C (20 mg), the mixture was stirred for 15 hours at room temperature in a hydrogen atmosphere. Insoluble matters were removed and the filtrate was concentrated in vacuo to give 3-(2-oxa-6-azaspiro[3.3]heptan-6-yl)aniline (100 mg, 98%). LC-MS: 191 [M+H]+, tR=0.99 min.

Provenance & Evidence