Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | HCID 59529889 | HCID 59529889 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 59529848 | HCID 59529848 | — |
Reaction Steps
N-Methylamine in MeOH (2 M, 2.0 mL, 4.0 mmol) was added to 2-chloro-N-cyclopentyl-4-fluoro-5-nitrobenzamide (230 mg, 0.79 mmol) in EtOH. The mixture was heated at 50° C. for 12 h in a sealed vessel, cooled and concentrated. The residue was purified by chromatography to give the sub-title compound. Yield: 150 mg (64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08921405B2 |
|---|
| Source dataset | uspto-grants-2014_12 |
|---|
| ORD ID | ord-e3fe52a968f54b01a435ce3fc5947f93 |
|---|
| Source note | uspto-grants-2014_12 |
|---|
