HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-amino-4-(methylamino)benzoate → Methyl 2-{5-[(tert-Butoxycarbonylamino)methyl]-2-chlorophenylamino}-1-methylbenzimidazole-5-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-amino-4-(methylamino)benzoate | HCID 15586064 | — |
| Reactant | tert-Butyl 4-chloro-3-isothiocyanatobenzylcarbamate | HCID 86646335 | — |
| Product | Methyl 2-{5-[(tert-Butoxycarbonylamino)methyl]-2-chlorophenylamino}-1-methylbenzimidazole-5-carboxylate | HCID 68509484 | — |
Reaction Steps
The sub-title compound was prepared from tert-butyl 4-chloro-3-isothiocyanatobenzylcarbamate (see Example 2d) and methyl 3-amino-4-methylaminobenzoate according to Example 3, step (g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921405B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-fd0011f550eb472e8bb0243ebbb91d87 |
| Source note | uspto-grants-2014_12 |