HCID 178481207, compound → HCID 178481208, compound

Participants

Reaction Steps

The sub-title compound was prepared in accordance with Example 3d, using 2-[(2-chloro-5-cyano-4-fluoro-phenyl)-amino]-6-(2,2-difluoroethoxy)-1-methyl-N-(trans-4-trifluoromethyl-cyclohex-1-yl)-1H-benzo[d]imidazole-5-carboxamide (210 mg; 0.37 mmol), Ra—Ni (3 mg), H2 (5 atm) and THF (10 mL). Yield: 150 mg (70%).

Provenance & Evidence