1,1'-Thiocarbonyldi-2(1H)-pyridone → HCID 87283320, compound

HRID 1410262Notes

Reaction equation

HRID 1410262 reaction equation
[C:1]([O:5][C:6](=[O:20])[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[C:11]([NH2:19])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[C:21](N1C=CC=CC1=O)(N1C=CC=CC1=O)=[S:22]>>[C:1]([O:5][C:6](=[O:20])[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[C:11]([N:19]=[C:21]=[S:22])[CH:10]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 8531621,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 59529859HCID 59529859, compound

Product 1

HCID 87283320HCID 87283320, compoundYield 86%

Procedure

The sub-title compound was prepared from tert.-butyl-N-(3-amino-4-trifluoromethyl-benzyl)carbamate with 1,1′-thiocarbonyldi-2-pyridone in analogy to example 1d.

Sources & evidence

ORD record
ord-725605c194244885a3111d61192e4a62
Source dataset
uspto-grants-2014_12
Patent number
US08921405B2

Reaction notes

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