HCID 178493230, compound → HCID 178493221, compound

HRID 1410264Notes

Reaction equation

HRID 1410264 reaction equation
[F:1][C:2]([F:25])([F:24])[C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10](=[O:23])[C:11]2[CH:16]=[C:15]([N+:17]([O-])=O)[C:14]([NH2:20])=[CH:13][C:12]=2[O:21][CH3:22])[CH2:5][CH2:4]1>[Ni]>[F:1][C:2]([F:24])([F:25])[C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10](=[O:23])[C:11]2[CH:16]=[C:15]([NH2:17])[C:14]([NH2:20])=[CH:13][C:12]=2[O:21][CH3:22])[CH2:5][CH2:4]1

Participants

3

Reactant 1

HCID 178493230HCID 178493230, compound

Product 1

HCID 178493221HCID 178493221, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The sub-title compound was prepared from N-(trans-4-trifluoromethyl-cyclohex-1-yl)-2-methoxy-4-amino-5-nitro benzoic acid amide with Ra—Ni in analogy to example 59g.

Sources & evidence

ORD record
ord-af7798d40bb74c18ad55998e1e24742c
Source dataset
uspto-grants-2014_12
Patent number
US08921405B2

Reaction notes

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