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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1410265Generated: November 1, 2026

O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate → HCID 178486905, compound

https://huagongshe.com/reaction/1410265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 2733207—
Reactant2-{[(Tert-butoxy)carbonyl]amino}-3,3,3-trifluoropropanoic acidHCID 53403782—
ReactantHCID 178486903HCID 178486903—
ProductHCID 178486905HCID 17848690570%

Reaction Steps

The title compound was prepared from 2-(5-aminomethyl-2-trifluoromethyl-phenylamino)-6-methoxy-N-(trans-4-trifluoromethyl-cyclohex-1-yl)-1H-benzo[d]imidazole-5-carboxamide and 2-tert.butoxycarbonylamino-3,3,3-trifluoro-propionic acid with TBTU, and TEA in THF_in analogy to example 3e.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921405B2
Source datasetuspto-grants-2014_12
ORD IDord-42a15a0cbdf441f882f6ea2ecc320ad3
Source noteuspto-grants-2014_12