HCID 178491191, compound → HCID 178491190, compound

HRID 1410271Notes

Reaction equation

HRID 1410271 reaction equation
[NH2:1][C:2]1[C:20]([NH2:21])=[CH:19][C:5]([C:6]([NH:8][C@H:9]2[CH2:14][CH2:13][C@H:12]([C:15]([F:18])([F:17])[F:16])[CH2:11][CH2:10]2)=[O:7])=[C:4]([Cl:22])[CH:3]=1.[N:23]([C:26]1[CH:27]=[C:28]([CH:37]=[CH:38][C:39]=1[O:40][CH3:41])[CH2:29][N-:30][C:31](=[O:36])[C:32]([CH3:35])([CH3:34])[CH3:33])=[C:24]=S>>[F:18][C:15]([F:16])([F:17])[C@H:12]1[CH2:11][CH2:10][C@H:9]([NH:8][C:6]([C:5]2[C:4]([Cl:22])=[CH:3][C:2]3[NH:1][C:24]([NH:23][C:26]4[CH:27]=[C:28]([CH2:29][NH:30][C:31]([C:32]([CH3:33])([CH3:35])[CH3:34])=[O:36])[CH:37]=[CH:38][C:39]=4[O:40][CH3:41])=[N:21][C:20]=3[CH:19]=2)=[O:7])[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 178491191HCID 178491191, compoundHCID 178507677HCID 178507677, compound

Product 1

HCID 178491190HCID 178491190, compound

Procedure

The compound was prepared from 4,5-diamino-2-chloro-N-(trans-4-trifluoromethyl-cyclohex-1-yl)-benzamide and N-(3-isothiocyanato-4-methoxy-benzyl)-pivaloylamide in analogy to example 72a.

Sources & evidence

ORD record
ord-1ed5148c7e1b49229de39bd58d3dd6eb
Source dataset
uspto-grants-2014_12
Patent number
US08921405B2

Reaction notes

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