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HRID1410348

反应详情

EQUATION

反应方程式

HRID 1410348 的结构方程式

REACTANTS

反应物

2
结构：CN1C(=O)/C(=C/c2ccc3c(I)n[nH]c3c2)c2ccccc21
HCID178481470

未命名化合物

结构：O=C1Nc2ccccc2[C@]12C[C@H]2c1ccc2c(I)n[nH]c2c1
HCID178517040

未命名化合物

PRODUCTS

生成物

1
结构：CN1C(=O)[C@@]2(C[C@H]2c2ccc3c(I)n[nH]c3c2)c2ccccc21
HCID178481340

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized according to the method of (1R*,2S*)-2-(3-iodo-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-one, except substituting (E)-3-((3-iodo-1H-indazol-6-yl)methylene)-1-methylindolin-2-one (545 mg, 1.36 mmol) to give the title compound as a 9:1 mixture of diastereomers (405 mg, 72%); MS ESI 416.0 [M+H]+, calcd for [C18H14IN3O+H]+ 416.03.

WORKUP

后处理

  1. customThe title compound was synthesized