HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-1,3-benzothiazol-5-ol → 3-Methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-1,3-benzothiazol-5-ol | HCID 14195013 | — |
| Reactant | 7-Benzothiazolol,2-amino-(9CI) | HCID 45077459 | — |
| Product | 3-Methoxyaniline | HCID 10824 | — |
| Product | Ammonium thiocyanate | HCID 15666 | — |
Reaction Steps
The two derivatives that are not commercially available (2-amino-benzothiazol-5-ol and 2-amino-benzothiazol-7-ol) can be obtained by cyclization of 3-methoxyaniline with ammoniumthiocyanate followed by demethylation with boron tribromide as outlined in the scheme below:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921546B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-94a8e9dd8be94194903ebcc2a621c6a5 |
| Source note | uspto-grants-2014_12 |