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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1410532Generated: November 2, 2026

(2E)-3-(2,3-Dihydro-5-benzofuranyl)-2-propenoic acid → HCID 57343917, compound

https://huagongshe.com/reaction/1410532

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2E)-3-(2,3-Dihydro-5-benzofuranyl)-2-propenoic acidHCID 5706572—
Reactant2-[4-(1H-Indol-3-yl)-cyclohexylamino]-2-piperidin-4-yl-acetamide dihydrochlorideHCID 67775194—
ProductHCID 57343917HCID 57343917—

Reaction Steps

The title compound was prepared from the product of Example 1, step J, and trans-3-(2,3-dihydrobenzofuran-5-yl)prop-2-enoic acid, by the method of Example 1, step K, giving a solid that was mostly the more polar cyclohexyl diastereomer by LCMS. Mass spectrum (LCMS, ESI pos.) calcd. for C32H38N4O3: 527 (M+H). Found: 527

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08921559B2
Source datasetuspto-grants-2014_12
ORD IDord-6e42bf0f0eee4142bea592da21ecd110
Source noteuspto-grants-2014_12