Acetate → 5-[4-[2-(6-Methoxy-2-pyridinyl)ethenyl]-2-phenylmethoxyphenyl]-1,1-dioxo-2-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-3-one

HRID 141107Notes

Reaction equation

HRID 141107 reaction equation
[Br:31][c:32]1[n:33][c:34]([O:38][CH3:39])[cH:35][cH:36][cH:37]1.[C:40]([P:41]([C:42]([CH3:43])([CH3:44])[CH3:45])[c:46]1[cH:47][cH:48][cH:49][cH:50][c:51]1-[c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1)([CH3:58])([CH3:59])[CH3:60].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:17]2[CH2:18][C:19](=[O:30])[N:20]([CH2:24][CH2:25][Si:26]([CH3:27])([CH3:28])[CH3:29])[S:21]2(=[O:22])=[O:23])[cH:11][cH:12][c:13]([CH:15]=[CH2:16])[cH:14]1.[CH3:61][C:62]#[N:63].[O-:65][C:66]([CH3:67])=[O:68].[O-:69][C:70]([CH3:71])=[O:72].[Pd+2:64]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([N:17]2[CH2:18][C:19](=[O:30])[N:20]([CH2:24][CH2:25][Si:26]([CH3:27])([CH3:28])[CH3:29])[S:21]2(=[O:22])=[O:23])[cH:11][cH:12][c:13]([CH:15]=[CH:16][c:32]2[n:33][c:34]([O:38][CH3:39])[cH:35][cH:36][cH:37]2)[cH:14]1

Participants

7

Reactant 6

HCID 175Acetate2×HCID 6342AcetonitrileHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 2568102-Bromo-6-methoxypyridineHCID 27342152-(Di-tert-butylphosphino)biphenylHCID 667565425-(2-Benzyloxy-4-vinylphenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 688381945-[4-[2-(6-Methoxy-2-pyridinyl)ethenyl]-2-phenylmethoxyphenyl]-1,1-dioxo-2-(2-trimethylsilylethyl)-1,2,5-thiadiazolidin-3-one

Sources & evidence

ORD record
ord-12a23c38acf840528ae35b0c317e7054
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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