HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → 2-(2-((6-Chlorohexyl)oxy)ethoxy)ethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-[2-(6-Chlorohexyloxy)ethoxy]ethylammonium trifluoroacetate | HCID 86671709 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2-((6-Chlorohexyl)oxy)ethoxy)ethanamine | HCID 10088464 | — |
Reaction Steps
To one equivalent of the succinimidyl ester of the reporter group in DMF is added 3 equivalence of 2-[2-(6-chlorohexyloxy)-ethoxy]-ethyl-ammonium trifluoro-acetate stock solution, followed by diisopropylethylamine. The reaction is stirred from 8 to 16 hours at room temperature. Purification is accomplished by preparative scale HPLC or silica gel chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08921620B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-de7eff52ebdc4c42bd477c7d79400eff |
| Source note | uspto-grants-2014_12 |