(4R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid → HCID 90449590, compound

Participants

Reaction Steps

The captioned compound was obtained in the form of a white solid by performing the same reactions and/or treatments as those in Example 19 and Step 2 of Example 117, with the exceptions that the 5-chloro-N-(5-chlorothiazol-2-yl)spiro[indoline-3,3′-pyrrolidine]-1-carboxamide obtained as an intermediate of Example 39 was used instead of 5-bromo-N-(5-chlorothiazol-2-yl)spiro[indoline-3,3′-pyrrolidine]-1-carboxamide, and that (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylic acid was used instead of N-Boc glycine.

Provenance & Evidence