Hydrochloric Acid → HCID 57113956, compound

Participants

Reaction Steps

In this example 0.02 mol of 1-(2-fluorophenyl)-3-methyl-5-(1,2-dichloroethyl)imino-1,3-diazolidine-2,4-dione is dissolved in 20 ml of acetonitrile and then 0.02 of mol of 2-chloroaniline is added. After about 10 minutes, triethylamine is added to neutralize the byproduct HCl produced by the reaction. The mixture is stirred for five hours and 20 ml of ethyl ether is then added. The mixture is filtered and the filtrate evaporated under high vacuum affording 1-(2-fluorophenyl)-3-methyl-5-(1-2'chlorophenylamino-2-chloroethyl)imino-1,3-diazolidine-2,4-dione.

Provenance & Evidence