反应详情

11.5 g of 2,5-dimethylpyridine-N-oxide in 5 ml of acetic acid were added dropwise to 18 ml of acetic anhydride pre-heated to 120°. The reaction solution was boiled under reflux for a further 45 minutes, concentrated by evaporation on a rotary evaporator, and distilled at 8 mm Hg/115°. 14.0 g of 2-acetoxymethyl-5-methylpyridine were obtained.

1. temperaturepre-heated to 120°
2. temperatureunder reflux for a further 45 minutes
3. concentrationconcentrated by evaporation on a rotary evaporator
4. distillationdistilled at 8 mm Hg/115°