HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 8-Methoxy-1,4-benzodioxane-5-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 8-Methoxy-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic Acid | HCID 22734248 | — |
| Product | 8-Methoxy-1,4-benzodioxane-5-carbonyl chloride | HCID 20544710 | 100.6% |
Reaction Steps
391 g of thionyl chloride and 138 g of 8-methoxy-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated to 50°-55° C. and the excess thionyl chloride was distilled off under vacuum. 151 g of 8-methoxy-1,4-benzodioxane-5-carbonyl chloride were obtained (yield: 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04248885 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-fef9e2953a5341c7a5a2bf01ac07d00f |
| Source note | uspto-grants-1981_02 |