HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 8-Acetamido-1,4-benzodioxan-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 8-Amino-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylic acid | HCID 21193470 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 8-Acetamido-1,4-benzodioxan-5-carboxylic acid | HCID 14956207 | 84% |
Reaction Steps
43 g of 8-amino-1,4-benzodioxane-5-carboxylic acid and 72 ml of acetic acid were introduced into a balloon flask and then 24.5 ml of acetic anhydride were added in portions. The mixture was heated to 60°-70° C. and then cooled. The precipitate was dried off, washed with acetic acid and water and dried. 44 g of 8-acetamino-1,4-benzodioxane-5-carboxylic acid were obtained (M.P.: 233° C.; yield: 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04248885 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-3fc86df0dcfe4f6b9f5a023155cd9ca6 |
| Source note | uspto-grants-1981_02 |