HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 5[(4-Methyl-1-piperazinyl)-carbonyl]-7-amino-1,4-benzodioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 7-Amino-2,3-dihydro-1,4-benzodioxine-5-carboxylic acid | HCID 20544752 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5[(4-Methyl-1-piperazinyl)-carbonyl]-7-amino-1,4-benzodioxane | HCID 20544730 | — |
Reaction Steps
In the same manner as described in Example 2, the 7-amino-1,4-benzodioxane-5-carboxylic acid was treated with the methanol, and then the obtained carboxylic ester was reacted with N-methyl piperazine. 5[(4-methyl-1-piperazinyl)-carbonyl]-7-amino-1,4-benzodioxane was obtained (M.P.: 170° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04248885 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-8d0f64db70864b3885350be97e461cd0 |
| Source note | uspto-grants-1981_02 |