(2-benzyl-1H-imidazol-4-yl)methanol → HCID 178519865, compound

HRID 1413257Notes

Reaction equation

HRID 1413257 reaction equation
[CH2:1]([C:8]1[NH:9][CH:10]=[C:11]([CH2:13][OH:14])[N:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH2:1]([C:8]1[NH:9][CH:10]=[C:11]([CH:13]=[O:14])[N:12]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 178519866(2-benzyl-1H-imidazol-4-yl)methanol

Product 1

HCID 178519865HCID 178519865, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6212ChloroformSolvent

Procedure

A 125 gm. portion of 2-benzyl-4-imidazolemethanol and 500 g. of manganese dioxide in 2 liters of chloroform are reacted as described in Example 22 giving the desired product, m.p. 130°-136° C.

Sources & evidence

ORD record
ord-a0d2982ef50a4c858c69e37c4e4ba61c
Source dataset
uspto-grants-1981_02
Patent number
USRE030511

Reaction notes

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