Sodium Hydroxide → 2-p-Chlorophenyl-2(2,3-dibromopropionyl)5-methoxymethyl oxazolidine

Participants

Reaction Steps

To 20.8 milliliters of 25 percent w/v, p-chlorophenyl-5-methoxymethyl oxazolidine solution in 50 milliliters of benzene was added 5 grams of 2,3-dibromopropionyl chloride. To this solution was added 1.6 grams of 50% sodium hydroxide. After washing with water, drying and removal of the benzene in vacuo, there was obtained 4.8 grams of the title compound, nD30 1.5478. Analytical data supports the structure.

Provenance & Evidence