4-Aminobenzoic Acid → HCID 20291876, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 3.78 g (0.02 mol) of 3-azidophthalic anhydride in 50 ml of dioxan is mixed with a solution of 2.74 g (0.02 mol) of p-aminobenzoic acid in 50 ml of dioxan and the mixture is left to stand for 3 hours. 5 ml of acetic anhydride are then added and the reaction mixture is heated for 1 hour at 85° C. After concentrating to dryness, the residue is mixed with water and the resulting crystals are filtered off with suction. 4.8 g (78% of theory) of 4-(3-azidophthalimidyl)-benzoic acid are obtained; melting point 300° C. (with decomposition).

Provenance & Evidence