反应详情

温度

80 °C

A mixture of 20.9 g (0.05 mol) of N-(1-ethyl-10,10-dimethyl-11-hydroxyundecyl)-3-nitrophthalimide and 3.55 g (0.055 mol) of sodium azide in 100 ml of dimethylsulphoxide is stirred for 24 hours at 80° C. The solution is evaporated in vacuo and the residue is diluted with 300 ml of water. The resulting emulsion is extracted with twice 100 ml of diethyl ether. The ether extracts are first dried with anhydrous sodium sulphate, and then evaporated. 14.7 g (71% of theory) of N-(1-ethyl-10,10-dimethyl-11-hydroxyundecyl)-3-azidophthalimide are obtained in the form of a viscous oil which cannot be distilled.

1. customThe solution is evaporated in vacuo
2. additionthe residue is diluted with 300 ml of water
3. extractionThe resulting emulsion is extracted with twice 100 ml of diethyl ether
4. dry with materialThe ether extracts are first dried with anhydrous sodium sulphate
5. customevaporated