2-Chlorobutanoyl chloride → HCID 20291855, compound

HRID 1413363Notes

Reaction equation

HRID 1413363 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[C:6]=2[CH:21]=1.[Cl:22][CH:23]([CH2:27][CH3:28])[C:24](Cl)=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]3[C:24]([CH:23]([Cl:22])[CH2:27][CH3:28])=[N:13][N:12]=[C:10]3[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=3[Cl:20])[C:6]=2[CH:21]=1

Participants

3

Reactant 2

HCID 1390532-Chlorobutanoyl chlorideHCID 123908757-Chloro-5-(2-chlorophenyl)-2-hydrazinyl-3H-1,4-benzodiazepine

Product 1

HCID 20291855HCID 20291855, compound

Procedure

In the manner given in Preparation 2, 7-chloro-5-(o-chlorophenyl)-3H-1,4-benzodiazepin-2-yl-hydrazine was reacted with α-chlorobutyryl chloride (CHE--CH2 --CHCl--COCl) to give 8-chloro-1-(α-chloropropyl)-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-122870771d954297b800c0b70ce09983
Source dataset
uspto-grants-1981_02
Patent number
US04250094

Reaction notes

Loading…