HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Dimethylamino)acetohydrazide → 1H-1,4-Benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Dimethylamino)acetohydrazide | HCID 68319 | — |
| Reactant | 1,3-dihydro-7-nitro-5-(o-chlorophenyl)-2H-1,4-benzodiazepine-2-thione | HCID 12371433 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1H-1,4-Benzodiazepine | HCID 148431 | — |
Reaction Steps
In the manner given in Example 5, a solution of 1,3-dihydro-7-nitro-5-(o-chlorophenyl)-2H-1,4-benzodiazepine-2-thione in n-butyl alcohol was heated to reflux with (dimethylamino)acetic acid hydrazide to give 8-nitro-1-[(dimethylamino)methyl]-6-(o-chlorophenyl)-4H-s-triazolo-[4,3-a][1,4-benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250094 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-287f20157cfd4571a3282b9ccab97389 |
| Source note | uspto-grants-1981_02 |