Glycine, N,N-dipropyl-, hydrazide → HCID 70575526, compound

HRID 1413368Notes

Reaction equation

HRID 1413368 reaction equation
[CH3:1][C:2]1[CH:22]=[CH:21][C:5]2[C:6]([C:12]3[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=3)=[N:7][CH2:8][C:9](=S)[NH:10][C:4]=2[CH:3]=1.[CH2:23]([N:26]([CH2:30][C:31]([NH:33][NH2:34])=O)[CH2:27][CH2:28][CH3:29])[CH2:24][CH3:25]>C(O)CCC>[CH3:1][C:2]1[CH:22]=[CH:21][C:5]2[C:6]([C:12]3[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=3)=[N:7][CH2:8][C:9]3[N:10]([C:31]([CH2:30][N:26]([CH2:27][CH2:28][CH3:29])[CH2:23][CH2:24][CH3:25])=[N:33][N:34]=3)[C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 17542Glycine, N,N-dipropyl-, hydrazideHCID 19865848HCID 19865848, compound

Product 1

HCID 70575526HCID 70575526, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

In the manner given in Example 5, a solution of 1,3-dihydro-8-methyl-5-(p-isopropylphenyl)-2H-1,4-benzodiazepine-2-thione in n-butyl alcohol was heated to a reflux with (dipropylamino)acetic acid hydrazide to give 9-methyl-1-[(dipropylamino)methyl]-6-(p-isopropylphenyl)-4H-s-triazolo[4,3-a][1,4)benzodiazepine.

Sources & evidence

ORD record
ord-913c346f93774f2ab8a7b16f3c27d65c
Source dataset
uspto-grants-1981_02
Patent number
US04250094

Reaction notes

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