Dimethylamine → HCID 12612384, compound

HRID 1413380Notes

Reaction equation

Cl[CH2:2][C:3]1[N:7]2[C:8]3[CH:22]=[CH:21][CH:20]=[CH:19][C:9]=3[C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:11][CH2:12][C:6]2=[N:5][N:4]=1.[CH3:23][NH:24][CH3:25]>>[CH3:23][N:24]([CH2:2][C:3]1[N:7]2[C:8]3[CH:22]=[CH:21][CH:20]=[CH:19][C:9]=3[C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[N:11][CH2:12][C:6]2=[N:5][N:4]=1)[CH3:25]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 12612381HCID 12612381, compound

Product 1

HCID 12612384HCID 12612384, compound

Procedure

In the manner given in Example 1, 1-(chloromethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine was reacted with dimethylamine to give 1-[(dimethylamino)-methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine of melting point 182°-183.5° C.

Sources & evidence

ORD record: ord-89d6a9e12f51460db23a12ebddfee04b
Source dataset: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04250094

Reaction notes

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