Benzylamine → HCID 54257956, compound

HRID 1413390Notes

Reaction equation

C(N)C1C=CC=CC=1.C(OC([NH:19][C@H:20]([C:23]([NH:25][C@H:26]([P:28](=[O:31])([OH:30])[OH:29])[CH3:27])=[O:24])[CH2:21][OH:22])=O)C1C=CC=CC=1>>[NH2:19][C@H:20]([C:23]([NH:25][C@H:26]([P:28](=[O:29])([OH:31])[OH:30])[CH3:27])=[O:24])[CH2:21][OH:22]

Participants

Reactant 2

HCID 7504Benzylamine

HCID 54491293HCID 54491293, compound

Product 1

HCID 54257956HCID 54257956, compound

Procedure

In a manner analogous to that described in Example 3(ii), from the monobenzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-L-seryl)amino]-ethylphosphonic acid there was obtained (1R)-1-(L-serylamino)-ethylphosphonic acid of melting point 250°-251° C. (decomposition); [α]D20 =-41.7° (c=0.5% in water).

Sources & evidence

ORD record: ord-483d103f7d5447fe85f2cc9c04d3240c
Source dataset: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04250085

Reaction notes

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