Benzylamine → HCID 54075437, compound

HRID 1413391Notes

Reaction equation

C(N)C1C=CC=CC=1.C(OC([NH:19][C@H:20]([C:22]([NH:24][C@H:25]([C:28]([NH:30][C@H:31]([P:33](=[O:36])([OH:35])[OH:34])[CH3:32])=[O:29])[CH2:26][OH:27])=[O:23])[CH3:21])=O)C1C=CC=CC=1>>[NH2:19][C@H:20]([C:22]([NH:24][C@H:25]([C:28]([NH:30][C@H:31]([P:33](=[O:34])([OH:36])[OH:35])[CH3:32])=[O:29])[CH2:26][OH:27])=[O:23])[CH3:21]

Participants

Reactant 2

HCID 7504Benzylamine

HCID 54420287HCID 54420287, compound

Product 1

HCID 54075437HCID 54075437, compound

Procedure

In a manner analogous to that described in Example 3(ii), from the monobenzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-L-alanyl-L-seryl)amino]-ethylphosphonic acid there was obtained (1R)-1-(L-alanyl-L-serylamino)-ethylphosphonic acid of melting point 234°-235° C. (decomposition).

Sources & evidence

ORD record: ord-63110f3910914c8ba01cecea806c3942
Source dataset: uspto-grants-1981_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04250085

Reaction notes

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