反应详情

127 parts of 1-nitroanthraquinone are suspended at room temperature in 1000 parts of dimethyl formamide. To this suspension are then added 35 parts of sodium azide. The reaction mixture is then stirred for 8 hours at room temperature and, after addition of 1000 parts of a mixture of ice and water, filtered. The filter cake is washed with water and the moist product (28% paste) is added in the course of 2 hours to 1000 parts of conc. sulfuric acid, taking care that the temperature does not rise above 85° C. The suspension is then heated to 95° C., stirred for 3 hours at 95°-100° C. and, after the dropwise addition of 400 parts of ice-water, filtered hot. The filtrate is then poured into 4000 parts of ice-water and filtered. The filter cake is washed neutral with water, affording 100 parts of 1-amino-4-hydroxyanthraquinone.

1. filtrationfiltered
2. washThe filter cake is washed with water
3. additionthe moist product (28% paste) is added in the course of 2 hours to 1000 parts of conc. sulfuric acid
4. customdoes not rise above 85° C
5. temperatureThe suspension is then heated to 95° C.
6. stirringstirred for 3 hours at 95°-100° C.
7. additionafter the dropwise addition of 400 parts of ice-water
8. filtrationfiltered hot
9. additionThe filtrate is then poured into 4000 parts of ice-water
10. filtrationfiltered
11. washThe filter cake is washed neutral with water