HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 10-Oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 6-chloropyridazine-3-carboxylic Acid | HCID 6415762 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 10-Oxo-10H-pyridazino[6,1-b]quinazoline-2-carboxylic acid | HCID 12665681 | — |
Reaction Steps
A precipitate is obtained when a mixture of methyl anthraniliate (4.78 g, 31.6 mmol), 6-chloropyridazine-3-carboxylic acid (5.0 g, 31.6 mmol) and 50 ml of acetic acid is heated at reflux for 21 hrs; m.p. 246°-50° C. This crude material is recyrstallized from pyridine giving the anlytical sample, m.p. 239°-43° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250177 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-43a0cc5fc4d2482e8a8dc283a00e828f |
| Source note | uspto-grants-1981_02 |