HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-bromobutanimide → 3-Bromo-2(methoxycarbonylamino)-6(phenylthio) imidazo [1,2-a] pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Methyl [6-(phenylsulfanyl)imidazo[1,2-a]pyridin-2-yl]carbamate | HCID 12414300 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Bromo-2(methoxycarbonylamino)-6(phenylthio) imidazo [1,2-a] pyridine | HCID 54463151 | — |
Reaction Steps
A suspension of 2-(methoxycarbonylamino)-6-(phenylthio) imidazo [1,2-a] pyridine (300 mg., 1 mmole) in 20 ml. of dichloromethane is treated with N-bromosuccinimide (220 mg., 1.24 mmole). The resultant solution is stirred at room temperature for 48 hours. The precipitate is collected by filtration, washed with dichloromethane and dried to yield 3-bromo-2-(methoxycarbonylamino)-6-(phenylthio) imidazo [1,2-a] pyridine m.p. 165°-168° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250174 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-9d42bcd3f1e14f78bf75188b0907eb7e |
| Source note | uspto-grants-1981_02 |