HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 20506365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | HCID 20506295 | HCID 20506295 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20506365 | HCID 20506365 | — |
Reaction Steps
To a stirred mixture of 19 parts of 2-(methylthio)-1H-benzimidazole-1-propanol, 15.2 parts of N,N-diethylethanamine and 195 parts of dichloromethane are added dropwise 11.5 parts of methanesulfonyl chloride. Upon completion, stirring is continued for one hour at reflux. After cooling, water is added and the layers are separated. The organic phase is dried, filtered and evaporated, yielding 3-[2-(methylthio)-1H-benzimidazol-1-yl]propyl methanesulfonate as an oily residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250176 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-f8c90e2de2984c5f9e6d61654e181883 |
| Source note | uspto-grants-1981_02 |