HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-aminobutanoate → methyl N-[N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyryl]-4-aminobutyrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-aminobutanoate | HCID 18614 | — |
| Reactant | Butyric acid, 4-(p-chloro-N-2,6-xylylbenzamido)- | HCID 35383 | — |
| Product | methyl N-[N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyryl]-4-aminobutyrate | HCID 20292236 | — |
Reaction Steps
Analogously to Example 1, by using equivalent quantities, reacting N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyric acid and methyl 4-aminobutyrate and suitable processing produces methyl N-[N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyryl]-4-aminobutyrate (oil), saponification of which and processing of the reaction product yields N-[N-(p-chlorobenzoyl)-4-(2,6-dimethylanilino)butyryl]-4-aminobutyric acid (M.P. 141° to 142°).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250183 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-c1138042fccb4ea1ab13d01323c9696e |
| Source note | uspto-grants-1981_02 |