Methyl 4-aminobutanoate → HCID 20292107, compound

HRID 1413585Notes

Reaction equation

HRID 1413585 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:23]=[C:24]([O:28][CH3:29])[C:25]=1[O:26][CH3:27])[C:6]([N:8]([CH2:17][CH2:18][CH2:19][C:20](O)=[O:21])[C:9]1[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:16])=[O:7].[NH2:30][CH2:31][CH2:32][CH2:33][C:34]([O:36][CH3:37])=[O:35]>>[CH3:29][O:28][C:24]1[CH:23]=[C:5]([CH:4]=[C:3]([O:2][CH3:1])[C:25]=1[O:26][CH3:27])[C:6]([N:8]([CH2:17][CH2:18][CH2:19][C:20]([NH:30][CH2:31][CH2:32][CH2:33][C:34]([O:36][CH3:37])=[O:35])=[O:21])[C:9]1[C:14]([CH3:15])=[CH:13][CH:12]=[CH:11][C:10]=1[CH3:16])=[O:7]

Participants

3

Reactant 2

HCID 18614Methyl 4-aminobutanoateHCID 20292172N-(3,4,5-trimethoxybenzoyl)-4-(2,6-dimethylanilino)butyric acid

Product 1

HCID 20292107HCID 20292107, compound

Procedure

Analogously to Example 1, by using equivalent quantities, reacting N-(3,4,5-trimethoxybenzoyl)-4-(2,6- dimethylanilino)butyric acid and methyl 4-aminobutyrate and suitable processing produces methyl N-[N-(3,4,5-trimethoxybenzoyl)-4-(2,6-dimethylanilino)butyryl]-4-aminobutyrate (M.P. 97° to 99°), saponification of which and processing of the reaction product yields N-[N-(3,4,5-trimethoxybenzoyl)-4-(2,6-dimethylanilino)butyryl]-4-aminobutyric acid (M.P. 100° to 101°).

Sources & evidence

ORD record
ord-a2ac3a7c642b4670bdb25c2d1f62da71
Source dataset
uspto-grants-1981_02
Patent number
US04250183

Reaction notes

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